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F. Nobile

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Open access Sep 2026

Estimating the PM2.5–Mortality Concentration–Response Function in the Rome Longitudinal Study (ROLS): A Methodological Comparison of Linear, Spline, and SCHIF Approaches

Introduction In health impact assessments (HIAs) of air pollution, a crucial issue is the correct specification of the concentration-response function (CRF) between exposure and outcome. Traditional approaches often assume a linear relationship, with the risk of introducing bias when the association is actually non-li...

A. Smimmo, F. Nobile, Paola Schiattarella et al. · 0 citations

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