Open access
Sep 2026
Age-related reduction in D-dimer cut-off specificity: Diagnostic relevance in geriatric patients.
INTRODUCTION D-dimer testing is widely used to exclude pulmonary embolism (PE), but its specificity declines sharply with age. Evidence in very old adults is limited, as most validation studies include few patients aged ≥80 years. This study aimed to identify and validate a clinically appropriate D-dimer threshold for...
F. Marchegiani, R. Galeazzi, L. Antognoli et al.
· Thrombosis Research · 0 citations