The Cre-lox system allows targeted expression of optogenetic proteins such as channelrhodopsin-2 (ChR2), but can also produce unintended expression in non-target cells. In a VGLUT1-Cre::ChR2(H134R)-eYFP mouse line, we bred mice that correctly expressed ChR2 in VGLUT1 positive neurons. This was corroborated with whole c...
Adeeb Akhavan, F. Moradpour, B. R. Christie et al.· Neuroscience· 0 citations
Opioid exposure during adolescence, a critical neurodevelopmental period, can impair adult cognitive function through lasting neurobehavioral changes. Here, the effects of sub-chronic adolescent exposure to morphine (SAEM) on anxiety, fear conditioning, and synaptic plasticity in the ventral hippocampal CA1 field in ad...
Fatemeh Khani, A. Pourmotabbed, Y. Fathollahi et al.· Physiology and Behavior· 0 citations
Nandrolone decanoate (ND) exposure has been associated with impairments in hippocampal-dependent learning and memory, potentially involving alterations in intracellular calcium signaling and Calcineurin protein expression. Given the distinct functional contributions of the dorsal hippocampus (dHPC) and ventral hippocam...
Romina Salmani, Samad Alimohammadi, F. Zarei et al.· Behavioral and Brain Functio...· 0 citations
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