Open access
Sep 2026
365. Association between CYP2D6 genotype and treatment outcomes in hospitalized patients with major depressive disorder: a retrospective cohort study
Abstract Background Cytochrome P450 2D6 (CYP2D6) is a highly polymorphic hepatic enzyme involved in the metabolism of many commonly prescribed antidepressants. Genetic variations in CYP2D6 leads to differences in drug metabolism, affecting plasma concentrations and potentially influencing treatment effectiveness and to...
A. Jeremić, A. P. Curcin, D. Joković et al.
· International Journal of Neu... · 0 citations