Open access
Aug 2026
Prevalence of MUTYH germline variants in Pediatric and Adolescent/Young Adult Patients with a Brain Tumor
Germline pathogenic and likely pathogenic variants (PV/LPV) in MutY DNA Glycosylase (MUTYH), a key gene in the Base Excision Repair (BER) pathway, are classically linked to MUTYH-associated polyposis (MAP) and colorectal cancer. Emerging evidence suggests that MUTYH variants, particularly monoallelic ones, may co...
S. Cipri, A. Cacchione, G. Del Baldo et al.
· Neuro-Oncology Pediatrics · 0 citations