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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

F. Krammer

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2 papers indexed here

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Open access Sep 2026

Broadly reactive antibodies against influenza B virus hemagglutinin neutralize and protect through distinct structural mechanisms

ABSTRACT Influenza B viruses contribute substantially to seasonal disease burden; however, the structural basis by which antibodies recognize the major glycoprotein hemagglutinin (HA) and mediate antiviral activity remains incompletely defined. Influenza B virus used to circulate as two antigenically distinct lineages,...

D. Bhavsar, Alesandro Civljak, Bruno Bonnettaz et al. · 0 citations
Jul 2026

Evaluating AlphaFold 3 immune complex structure prediction and cryo-EM analysis of broadly neutralizing antibodies towards influenza hemagglutinin 2309571

Evaluated the accuracy of AlphaFold 3 (AF3) in predicting immune complexes of a known class of bnAbs towards a conserved epitope on influenza hemagglutinin (HA) and resolved atomistic details with high-resolution SPA cryo-EM that explain challenges with AF3 immune complex prediction.

Morgan Gee, Pragati Sharma, Alesandra J. Rodriguez et al. · 0 citations

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