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Author

F. Kozielski

2 papers indexed here

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Review Open access Sep 2026

From chemical space to synthetic reality: A framework for makeable-by-design generative AI in drug discovery.

Generative artificial intelligence (AI) is reshaping molecular design, but many outputs are still judged by proxy metrics that do not establish whether proposed compounds can be synthesized, tested and advanced. This review reframes the field around 'synthetic reality': the extent to which AI-generated molecules surviv...

Sebastián O. Simonetti, Aldana B. Moroni, M. Zanardi et al. · 0 citations
#protein folding Open access Sep 2026

Solution structure, dynamics and fragment binding of unbound MERS-CoV nsp10

Middle East Respiratory Syndrome Coronavirus (MERS-CoV) poses a significant public health threat, with a fatality rate of 37% and no approved therapeutics (World Health Organization, 2026). Non-structural protein 10 (nsp10) is an essential cofactor that activates both the nsp14 3’-5’ exoribonuclease (ExoN) activity req...

D. Dong, F. Kozielski, Christopher A. Waudby · 0 citations

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