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Author

F. Kolling

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Open access Jul 2026

Epithelial-mesenchymal transition is associated with altered immune composition and cytotoxic function in triple-negative breast cancer

Findings reveal that EMT is associated with immune cell recruitment and function in a graded manner, providing a rationale for integrating EMT phenotyping into therapeutic strategies to overcome immune resistance in breast cancer.

Han-Xu Lu, Meisam Bagheri, F. Kolling et al. · 0 citations
Jul 2026

PI3K Delta Inhibition Alters CD8 T Cell Différentiation and Reprograms the Tumor Microenvironment Following Adoptive Immunotherapy 2247548

PI3Kδ inhibition programs T cells with stemness and metabolic fitness that favor Tpex differentiation, resist terminal exhaustion, and remodel the TME toward an inflammatory state, supporting a practical strategy to improve ACT efficacy in solid tumors.

Alexandrea Turnquist, Azka Javaid, F. Kolling et al. · 0 citations

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