Open access
Sep 2026
Transcriptomic Architecture of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) Risk in Mexican Americans
Highlights What are the main findings? Hepatic steatosis (neutral lipid) measures in iPSC-derived hepatocyte cultures showed statistically significant additive genetic heritability at baseline (h2 = 0.44, p ≤ 0.05) and post-lipid challenge (h2 = 0.42, p ≤ 0.05). Transcriptome-wide association analysis identified 1070 g...
Satish Kumar, Miriam Aceves, Lorena Guerra et al.
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