Open access
Oct 2026
ClonoDeconv: reference-based α − β paired recurrent clonotype proportion estimation from bulk-TCR sequencing
T cell receptor (TCR) sequencing is crucial when studying antigen-specific T cell responses and clonal dynamics. A key objective of TCR repertoire analysis is to identify recurring clonotypes across timepoints or different disease states, providing insight into the evolution of immune response. Bulk-TCR sequencing enab...
Yu-Ze Zhou, E. Antoun, M. Pinho et al.
· bioRxiv · 0 citations