Author

F. Iannotta

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Open access Sep 2026

181. Integrating clinical profiles and microRNAs to uncover molecular mechanisms in treatment-resistant schizophrenia

Abstract Background Treatment-resistant schizophrenia (TRS), defined as the persistence of symptoms despite adequate antipsychotic treatment, remains frequently underrecognized, with clozapine, the gold standard, introduced only after an average delay of 4–9 years. In this study, we aimed to identify which Positive and...

L. Vellucci, P. Mirra, A. Nasti et al. · International Journal of Neu... · 0 citations

Review Open access Sep 2026

Addressing fusiform gyrus dysfunction in schizophrenia, theory of mind, and implications for antipsychotics' response and resistance: A systematic review and critical appraisal.

BACKGROUND The Fusiform Gyrus (FG), a brain region relevant for the interaction between cognitive processes and emotional behavior, especially emotion recognition and interpretation of social cues, has been linked to the pathophysiology of schizophrenia conceptualized as a disorder of aberrant synaptic function and bra...

M. Ciccarelli, B. Mazza, A. Nasti et al. · Neuroscience and Biobehavior... · 0 citations

Case report Open access Jul 2026

Case Report: Early-onset psychosis as a sentinel manifestation of 3q29 deletion syndrome in an adolescent with neurodevelopmental disorders

Early-onset psychotic symptoms in adolescents with neurodevelopmental comorbidities may represent a critical clinical indicator of underlying pathogenic copy number variants, including 3q29 deletion syndrome, even in the absence of highly recognizable dysmorphic features.

E. Bartolini, Federica Iannotta, W. Vidal et al. · Frontiers in child and adole... · 0 citations