Establishment of Uveal Melanoma Patient-Derived Organoids Using an Air–Liquid Interface System for Translational Research
Purpose Uveal melanoma (UM) is the most common primary intraocular malignancy in adults, with a unique genetic and epigenetic profile and a high metastatic risk. The lack of experimental models to replicate tumor biology, including its epigenetic landscape, limits progress in translational research. Recently, patient-d...