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Author

F. Ciceri

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Oct 2026

GvHD prophylaxis in elderly patients: post-transplant cyclophosphamide or ATG? A study by the EBMT transplant complications working party.

It is indicated that PTCy is a safe and effective alternative to ATG in older allo‑HCT recipients, especially in MUD transplants and in MSD recipients aged >65 years, but the findings should be interpreted cautiously given their observational nature and patient heterogeneity.

L. K. Gjærde, C. Peczynski, W. Boreland et al. · 0 citations
Open access Sep 2026

Therapy induced senescence promotes immunogenicity in acute myeloid Leukemia through reduced EZH2 activity

Chemotherapy resistance and disease relapse are major determinants of treatment failure in acute myeloid leukemia (AML). Therapy-induced senescence (TIS) is one outcome of chemotherapy, but its immunological consequences in AML remain unclear. Here we show that ex vivo chemotherapy induces senescence in a subset of the...

Diego Gilioli, Simona Fusco, Teresa Tavella et al. · 0 citations
Clinical trial Sep 2026

Etuvetidigene Autotemcel for the Treatment of Wiskott-Aldrich Syndrome.

BACKGROUND Wiskott-Aldrich syndrome is a rare, X-linked, life-threatening inborn error of immunity and platelet disorder caused by variants in the gene WAS. Etuvetidigene autotemcel (etu-cel) is an autologous gene therapy consisting of hematopoietic stem and progenitor cells that have been transduced ex vivo with a len...

F. Ferrua, S. Cenciarelli, S. Giannelli et al. · 0 citations
Open access Aug 2026

Mitigating HLA Disparity in AML Transplantation: Comparable Outcomes After Haploidentical and 9/10 Mismatched Unrelated Donor Transplantation With Treosulfan and PTCy

It is suggested that, within a treosulfan–PTCy platform, major transplant outcomes are comparable between donor types, although haploidentical transplantation was associated with a higher incidence of chronic GVHD.

D. Avenoso, M. Farina, M. Malagola et al. · 0 citations
Open access Sep 2026

A CREATE-Based Educational Intervention to Improve Evidence-Based Practice Competencies in a Low-Income Country: A Feasibility Pilot Study

This pilot study suggests that a CREATE-based teaching strategy delivered through synchronous distance learning is feasible and may improve EBP competencies among nurses and nursing students in Sudan, despite the challenges of a resource-constrained and conflict-affected setting.

Ilaria Marcomini, Federica Buzzi, Andrea Poliani et al. · 0 citations

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