Review
Open access
Oct 2026
BACKGROUND AIMS
To evaluate safety and efficacy of FGFR1-3 kinase inhibitor derazantinib, in advanced intrahepatic cholangiocarcinoma (iCCA) harboring FGFR2 fusions or rearrangements (FGFR2F), mutations (FGFR2M), or amplifications (FGFR2A), previously treated with chemotherapy.
APPROACH RESULTS
Open-label, non-contro...
M. Borad, Michele Droz Dit Busset, M. Javle et al.
· Hepatology · 0 citations
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Open access
Sep 2026
The objective of this study is to explore and validate a novel prognostic index for patients with locally advanced or metastatic biliary tract cancer (BTC) treated with first‐line therapy with cisplatin, gemcitabine, and durvalumab.
M. Persano, A. Casadei-Gardini, L. Fornaro et al.
· Cancer · 0 citations
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Sep 2026
In LARC, CRT reshapes the type and amount of immune cell contents, and the effects on certain immune populations are associated with tumor regression and clinical outcome.
Francesca Negri, L. Bottarelli, L. Gnetti et al.
· JCO Precision Oncology · 0 citations
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Review
Open access
Aug 2026
Simple Summary Squamous cell carcinoma of the anal canal (SCAC) is a rare malignancy whose incidence has been increasing worldwide. The main etiological factor is HPV infection, particularly in association with HIV infection and other immunosuppressive conditions. The majority of patients present with localized disease...
Matilde Callegarin, Valentina Angerilli, J. Gasparello et al.
· Cancers · 0 citations
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