Cadmium (Cd) is an environmentally pervasive toxic metal that accumulates in the kidney and promotes oxidative stress, inflammation, and apoptosis. This study evaluated the renoprotective effects of free pterostilbene (PTS) and PLGA-encapsulated PTS (PTS-PLGA) in male Sprague–Dawley rats with Cd-induced nephrotoxicity....
Fahd Alaajam, E. Elmorsy, Amro Duhduh et al.· Toxics· 0 citations
Background/Objectives: Oxidative stress, chronic inflammation, disrupted apoptosis, and altered autophagy are biological processes implicated in colorectal tumor development. Morin is a plant-derived flavonoid with antioxidant and anti-inflammatory properties, but its limited solubility and bioavailability may limit it...
Mohammed A. Akeel, E. Elmorsy, F. Alshammari et al.· Pharmaceuticals· 0 citations
HES and HES-PLGA-NPs were associated with multi-mechanistic protection against cisplatin-induced oxidative, inflammatory, apoptotic, and ferroptosis-associated damage in the testes, and may represent a promising nanoantioxidant candidate warranting further investigation for preserving male reproductive function during...
Mohammed A. Akeel, E. Elmorsy, Aly A. M. Shaalan et al.· Antioxidants· 0 citations
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