Development of a hybrid micelle--hydrogel system for topical delivery of doxorubicin to skin cancer cells
Objective(s): Topical delivery of anti-neoplastic agents could circumvent many drawbacks of chemotherapy in skin cancer. This study aims to develop a hybrid Hyaluronic acid-oleic acid (HA-C18) micelle--alginate hydrogel as a topical system for doxorubicin (DOX), enhancing skin penetration, providing controlled release,...