Renoprotective Effects of Vortioxetine in Experimental Renal Ischemia–Reperfusion Injury: An Investigation of Oxidative Stress, Inflammation, and Apoptotic Signaling
Renal ischemia–reperfusion (I/R) injury is a leading cause of acute kidney injury and is driven by oxidative stress, sterile inflammation, and regulated cell death. Vortioxetine (VOR), a multimodal antidepressant, carries anti-inflammatory and antioxidant activity beyond its neuropsychiatric actions, but has not been t...