Eveline H. Tiekink

Intrinsic charge polarization governs hydrogen-bonding strength in amide vs. imide self-association

The weaker self-association of imide dimers relative to amide dimers is often attributed to repulsive secondary electrostatic interactions (SEI) between diagonally positioned carbonyl groups. Quantification of the SEI interactions using quantum chemical analyses reveals that they are negligible and do not explain the s...