Author

Evan G. Williams

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Open access Jul 2026

Complex assembly and activity states as multifaceted protein attributes explaining phenotypic variability.

A multi-omics framework that infers context-specific protein activities from transcriptomic, phosphoproteomic, and protein correlation-based protein-protein interaction data is introduced, integrating modality-specific algorithms via network diffusion.

George A. Rosenberger, Peng Xue, Isabell Bludau et al. · Molecular Systems Biology · 0 citations

Open access Aug 2026

Systems genetics approaches model the heritable architecture of polyendocrine metabolic ovarian syndrome.

It is shown that increased ovarian area contributes to both PMOS susceptibility and ovarian cancer progression, while specific ovary-heart signaling circuits modulate cardiac function with aging, and SF3B1-mediated splicing is uncovered as a link between ovary function and systemic metabolism.

Christy M. Nguyen, L. Velez, Youngseo Cheon et al. · Journal of Clinical Investig... · 0 citations