Open access
Oct 2026
Avidity-controlled biotherapeutic delivery systems for the treatment of ischemia-reperfusion acute kidney injury
Regulatory T cells (Tregs) are key mediators of immune resolution and tissue repair following acute kidney injury (AKI), yet strategies to selectively enrich Tregs within the renal microenvironment remain limited. Interleukin-2 (IL-2) is essential for Treg survival and function, but systemic IL-2 delivery is constraine...
Arielle M. D'Elia, K. Kim, Alleé Shaw et al.
· bioRxiv · 0 citations