Cohesin, a ring-shaped SMC complex, mediates sister-chromatid cohesion, DNA repair, and genome folding via loop extrusion. Pluripotent and somatic cells were thought to rely solely on mitotic cohesin (SMC1A, SMC3, RAD21, STAG1/STAG2), while meiosis-specific subunits (SMC1B, REC8, STAG3) were considered germline-restric...
Min-Cho Soo, Young Eun Kim, Eui-Hwan Choi· Molecular Therapy: Nucleic A...· 0 citations
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