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Author

Eugenia A. Gurylina

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Review Open access Aug 2026

Overcoming the Limitations of Protein A: Evolution of Bacterial Protein-Based and Synthetic Affinity Ligands for High-Performance IgG Purification

Monoclonal antibodies (mAbs) are widely used as therapeutic molecules for the treatment of serious diseases, primarily cancer. The market for mAbs is one of the fastest-growing segments of the biopharmaceuticals industry. Purification is a crucial stage in the production of mAbs. While staphylococcal protein A (SpA) af...

L. N. Ikryannikova, M. N. Tereshin, Milena V. Baskova et al. · 0 citations

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