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Author

Ethan P. Cisneros

2 papers indexed here

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Open access Aug 2026

Surface chemistry governs sex-dependent responses to PEG and zwitterionic siRNA nanocarriers in primary macrophages

Nanoparticle carriers are widely used for nucleic acid delivery, with poly(ethylene glycol) (PEG)–conjugated nanoparticles emerging as a frontrunner in the field. Growing concerns surrounding PEG immunogenicity have generated interest in zwitterionic polymers as alternative biocompatible surface grafts. At present, the...

Olivia L. Lanier, Brinkley A. Morse, Ethan P. Cisneros et al. · 1 citation
Review Open access Sep 2026

Chemical and Biological Determinants of PEG-Lipid Shedding From Therapeutic Nanoparticles.

Key factors that link PEG-lipid composition and nanoparticle architecture to desorption kinetics and biological outcomes are identified and provide guidance for the design of PEGylated nanomaterials with improved control over interfacial stability, immune recognition, and functional performance.

Ethan P. Cisneros, Aadya S. Wijesekera, Lisa R. Volpatti · 0 citations

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