Eslam M. Hosni

Benzo[h]quinoline-based heterocyclic derivatives as Culex pipiens larvicidal candidates: synthesis, bioactivity, biochemical response, and in silico mechanistic insights.

Biochemical evaluation of triazinone 3 revealed significant reductions in acetylcholinesterase activity and in total protein, carbohydrate, and lipid contents compared with untreated larvae, indicating that larval mortality was accompanied by cholinergic disturbance and depletion of metabolic reserves.