#protein folding
Sep 2026
The Long Splice Variant of Ribosomal Protein S24 Protects Cells from Stress and Is Induced by AMPK-ULK1-Regulated Autophagy Independent of mTORC1
This study shows that an allosteric activator of AMPK is sufficient to induce RPS24L and autophagy in normoxia in an ULK1-dependent, but mTORC1-independent manner and interacts with RPS24 mRNA and its autophagy-dependent decrease shifts splicing toward the RPS24L variant.
Run-Qi Qian, Jenna Goodbrand, Shannon N. Adams et al.
· Biochemistry · 0 citations