Erin L. Ramsey

Communication is key: combinatorial phosphorylation and functional cross-talk in the RNA polymerase II CTD code

Abstract The C-terminal domain (CTD) of the largest subunit of RNA polymerase II serves as a dynamic platform coordinating transcription and RNA processing. Recent advances in mass spectrometry, structural biology, and sequencing approaches have revealed a far more complex, combinatorial CTD code than previously apprec...