SUMMARY
Most human genes produce multiple RNA isoforms, yet it remains unclear which isoforms are translated into stable, functional proteins. Long-read RNA sequencing resolves full-length transcript structures and, when paired with mass spectrometry, can provide empirical evidence of isoform translation. Despite this...
Megan D. Schertzer, Julia T. Lewandowski, Emily F. Watts et al.· Bioinformatics· 0 citations
Spermiogenesis, the transformation of round spermatids into streamlined, fertilization-competent sperm, represents cellular morphogenesis at its most extreme1,2. Despite decades of effort, spermiogenesis remains difficult to recapitulate outside the testis2,3, highlighting the importance of cues within the native tissu...
Wenhao Zheng, Lorena Roa-de la Cruz, John Duncan et al.· bioRxiv· 0 citations
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