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Author

Erika L. Loredo-Calderón

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Review Open access Oct 2026

Overview of screening assays used to evaluate PROTACs for cancer treatment.

Proteolysis-targeting chimeras (PROTACs) are promising anticancer agents, but optimizing them requires screening strategies that go beyond simple target-degradation readouts. This review provides an overview of assays for evaluating anticancer PROTACs and classifies them by their role in the degradation pathway, includ...

Raghd Obidat, Jazmin Reyes-Martinez, Sara Alrawashdeh et al. · 0 citations

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