PRIME: A modular plasmid-based platform for continuous in vivo evolution across bacteria
Protein-primed Replication for In vivo Mutagenesis and Evolution, a plasmid-based orthogonal DNA replication system for continuous directed evolution in Escherichia coli, provides a broadly accessible framework for continuous in vivo evolution, with wide-ranging applications in protein engineering and synthetic biology...
Erik Dechant, Lena K. Träger, S. Sikanjic et al.
· bioRxiv · 0 citations