Aug 2026
The mechanism of SOX4/IGF2BP3/TRIB3 axis inhibiting autophagy and aggravating liver injury in sepsis.
It was found that the SOX4/IGF2BP3/TRIB3 axis was upregulated in septic hepatocytes, and its knockdown alleviated LPS-induced injury and impaired autophagic flux, and this axis exacerbated LPS-induced hepatocyte injury by suppressing autophagic flux.
Wen-Jun Zhao, Jing Zhang, Liang Zhang et al.
· Biochimica et biophysica act... · 0 citations