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Author

Er-Li Song

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Open access Sep 2026

DNA damage repair gene defects combined predict the efficacy of immune checkpoint inhibitors in metastatic castration-resistant prostate cancer: a retrospective cohort study

Background Immune checkpoint inhibitors (ICIs) yield heterogeneous benefit in metastatic castration-resistant prostate cancer (mCRPC), underscoring the unmet need for robust predictive biomarkers. DNA damage repair (DDR) gene defects encompass mechanistically distinct subtypes—homologous recombination repair (HRR) defi...

Ke-Song Qin, Gang-Qiang Hu, Er-Li Song · 0 citations

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