Author

Eoin Casey

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#protein folding Open access Oct 2026

What drives the cost of biowaste-to-lipase production? Linking titre, rate and yield to techno-economic performance in batch-to-continuous Pichia pastoris fermentation

Fruit and vegetable (FV) waste represents an underutilized organic stream in Europe, yet its soluble sugar fraction remains poorly exploited as a bioprocess feedstock. Recombinant enzyme production from biowaste is often bottlenecked by heterogeneous substrate composition, low fermentable sugar titres, and uncertain pr...

Ana G. Del Hierro, Violine Raynal, Ruth Ordóñez et al. · Bioresources and Bioprocessi... · 0 citations

Open access Aug 2026

Unmasking Glycoforms: Lectin-Based Profiling and Functional Implications of Targeted Glycosylation Knockouts in Chinese Hamster Ovary Cells.

Monoclonal antibody (mAb) glycosylation is a critical quality attribute that is difficult to rationally engineer and rapidly assess during cell line development. Here, we investigate whether cell-surface glycosylation can serve as a surrogate readout of mAb product glycosylation following targeted glycogene engineering...

Cristina Abascal Ruiz, Sheryl Y. T. Lim, J. Brink et al. · Biotechnology and Bioenginee... · 0 citations