Author

En-Qiang Linghu

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Review Open access Aug 2026

Rapid, label-free differentiation of benign and malignant gastric lesions using two-photon microscopy and quantitative collagen analysis

Abstract Background and Objectives Previous investigations have explored two-photon microscopy (TPM) for differentiating normal and malignant lesions in the digestive tract. The aim of this study is to evaluate label-free TPM for rapid, ex vivo classification of fresh endoscopic human gastric tissues across the spectru...

Bo Ning, Xiaoqing Zhou, Kai-Yue Guan et al. · Journal of Translational Int... · 0 citations

Open access Sep 2026

Construction of an Esophageal Cancer Prognostic Model Based on Mitochondrial Energy Metabolism-Related Genes and Mechanism of INHBA in Promoting Malignant Progression via the Smad2/3 Pathway

Objective: Esophageal cancer (ESCA) has poor prognosis and lacks reliable biomarkers. This study aimed to construct a mitochondrial energy metabolism-related prognostic model and identify key regulatory genes. Methods: TCGA-ESCA and GSE53625 data were used as training and validation cohorts, respectively. Mitochondrial...

Jin-Ping Li, Yi Yao, Hui-Kai Li et al. · Biomolecules · 0 citations

Open access Jul 2026

Unveiling the aging-immune axis in irritable bowel syndrome: a multi-omics and machine learning approach to biomarker discovery and validation

Immune infiltration analysis uncovered a distinct immune landscape in IBS, with significant correlations between biomarker expression and immune cell populations, with significant correlations between biomarker expression and immune cell populations.

Yi Yao, Jingping Li, Bo Zhang et al. · Frontiers in Immunology · 0 citations