En-Hui Zhou

The mediating role of cardiac autonomic imbalance in the association between hypoxic burden and dyslipidemia in obstructive sleep apnea

Abstract Background Obstructive sleep apnea (OSA) is associated with cardiac autonomic dysfunction and impaired lipid homeostasis. We investigated whether cardiac autonomic imbalance mediates the association between hypoxic burden (HB) and dyslipidemia. Methods Between January 2022 and March 2026, we consecutively enro...

Treatment of Severe Obstructive Sleep Apnea With a Domestic Implantable Hypoglossal Nerve Stimulator: A Case Report

ABSTRACT Background Implantable hypoglossal nerve stimulation (HNS) is an established neuromodulatory therapy for obstructive sleep apnea (OSA) in patients intolerant to continuous positive airway pressure (CPAP). However, no domestically developed HNS system has been clinically implemented in China to date. Methods We...

Global Burden of Key Components of Cardiovascular–Kidney–Metabolic Syndrome Among Women of Reproductive Age, 1990–2021

Cardiovascular–kidney–metabolic (CKM) syndrome links metabolic, kidney, and cardiovascular disorders, but its burden among women of reproductive age (WRA) remains poorly understood. We quantified the global burden and trends of key CKM‐related conditions and high body mass index (BMI)‐attributable burden among WRA.

[Microstructural characteristics of sleep electroencephalogram in obstructive sleep apnea].