Towards a Novel Diagnostic Tool for Autoimmune Rheumatic Diseases: Classification of SLE Using FTIR Spectroscopy and Machine Learning
Background/Objective: Systemic lupus erythematosus (SLE) is a complex autoimmune disease with clinical and serological heterogeneity. Current laboratory assays show variable performance for disease detection and risk stratification, resulting in diagnostic delays exceeding six years. There is an unmet need for improved...