Substrate specificity in lipoylation pathways: How lipoate:protein ligases discriminate between protein substrates
Lipoate is an essential protein-bound cofactor attached to conserved lysine residues in structurally related acceptor proteins, including GcvH of the glycine cleavage system and LbpA proteins required for sulfur oxidation by the sulfur-oxidizing heterodisulfide-like (sHdr) complex. The coexistence of distinct lipoylati...
Carolin Kümpel, Emma Holz, Tomohisa Sebastian Tanabe et al.
· bioRxiv (Cold Spring Harbor... · 0 citations