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Emma A. Khachatryan

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Open access Oct 2026

Ni(II)-Mediated Asymmetric Synthesis of a Conjugated Diyne-ContainingNon-Proteinogenic Amino Acid via Glaser Heterocoupling

Non-proteinogenic amino acids bearing acetylenic motifs are valuable building blocks in medicinal chemistry and chemical biology due to their structural rigidity, synthetic versatility, and biological relevance. Herein, we report an asymmetric synthesis of (S)-2-amino-8-(3,4-dihydroisoquinolin-2(1H)-yl)octa-4,6-diynoic...

Emma A. Khachatryan · Reports of NAS RA · 0 citations