Further characterization of oral fentanyl self-administration in male and female Sprague Dawley rats.
Fentanyl is a potent synthetic opioid with high misuse potential and risk for overdose. While primarily associated with the intravenous route of administration, fentanyl is now often found in pills. However, few preclinical studies have assessed oral self-administration of fentanyl. In the present study, different grou...