Clinical features and outcomes of pediatric breakthrough invasive pneumococcal disease (IPD) in vaccinated children in Calgary, Alberta, Canada, 2003-2024.
BACKGROUND Since the introduction of pneumococcal conjugate vaccines (PCV7 in 2002 and PCV13 in 2010) in Alberta, the overall burden of invasive pneumococcal disease (IPD) in children has declined. However, vaccine-type invasive pneumococcal disease (VT-IPD) continues to occur, including in vaccinated children. METHO...