Elvira Bonilla-Toyos

Proof-of-concept phase II study protocol to evaluate the efficacy and safety of prednisone in the treatment of idiosyncratic hepatotoxicity and its mechanistic pathways through an integrative analysis: the DILICORT clinical trial

Idiosyncratic drug-induced liver injury (DILI) is an unpredictable adverse reaction ranging from mild liver enzyme elevations to acute liver failure, with management largely limited to withdrawal of the causative drug. An international propensity score-matched study of 724 DILI cases associated corticosteroid thera...