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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

Author

Elnaz Aledavood

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Open access Aug 2026

Screening of candidate antiparasitic drugs against Sparicotyle chrysophrii: A phenotypic drug discovery approach.

A phenotypic screening approach was applied to identify compounds active against S. chrysophrii, and niclosamide, one of the most potent compounds identified, demonstrated a parasiticidal activity more than 11,000-times greater than praziquantel, a reference chemotherapeutic agent commonly used against fish polyopistho...

Ana León, Teresa Pirollo, Elnaz Aledavood et al. · 0 citations
Open access Jul 2026

AI-assisted fragment-based drug discovery of SARS-CoV-2 macrodomain binders validated by NMR and X-ray crystallography.

This study demonstrates the advantages of integrating AI with FBDD to streamline molecular design, providing a data-driven framework for discovering new Mac1 inhibitors and guiding future antiviral drug development.

Elnaz Aledavood, Sandra Ramos-Inza, Jannis Born et al. · 0 citations
Open access Jul 2026

Selective Brain-Penetrant TTBK1 Inhibitors Modulate TDP-43 Pathology and Rescue Cognitive Deficits in a Mouse Model of TDP-43 Proteinopathy

It is found that these inhibitors reduce TDP-43 phosphorylation levels in neuroblastoma cells and FTD patient-derived models, and restores cognitive deficits, conferred neuroprotection in the frontal cortex, and reduced microglial activation in an FTD-TDP mouse model, supporting its therapeutic potential.

Cecilia Sanchez-Santos, Alberto Jiménez-Amor, Loreto Martínez-González et al. · 0 citations

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