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Ellie H. Northall

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Open access Sep 2026

CD248/Endosialin regulates synovial fibroblast state to control coupling of inflammation and bone damage in murine models of immune-mediated inflammatory arthritis and ageing.

OBJECTIVE Synovial fibroblasts directly contribute to inflammation and damage in immune-mediated inflammatory arthritis. CD248/Endosialin is expressed by fibroblasts in the synovium, is highly upregulated during inflammation and has been proposed as a potential therapeutic target. This study aimed to map the expression...

Samuel Kemble, C. Wehmeyer, James M. Brown et al. · 0 citations

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