Ellen O'Connor

A Process Selection Framework for Purifying Rat IgG1 Monoclonal Antibodies from Hybridoma Culture Supernatants: CaptureSelect IgG-Fc for Speed and POROS 50 HS-Capto Q for Scale.

Efficient purification of rat-derived antibodies is an ongoing challenge in biologics development, particularly for isotypes that are difficult to capture using conventional affinity methods. Traditional Protein A/G affinity resins often exhibit limited efficiency and scalability for rat antibodies, particularly rat Ig...