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Author

Elizabeth Gondowardojo

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Review Open access Oct 2026

Mesenchymal Stem Cell-Derived Paracrine Products as Senotherapeutic Interventions for Skin Photoaging: A Preclinical Systematic Review of the Senescence-SASP Axis

Chronic ultraviolet (UV) exposure induces oxidative stress, mitochondrial dysfunction, DNA damage, and cell cycle arrest through the p53/p21^CIP1^ and p16^INK4a^ pathways, contributing to cellular senescence and the development of the senescence-associated secretory phenotype (SASP). Objective: This study aimed to synt...

Elizabeth Gondowardojo, D. Wihandani, M. Setiawan · 0 citations

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