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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Elizabeth A. Thompson

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Open access Sep 2026

Balancing lipid synthesis and oxidation promotes B cell response to vaccination during immunosuppression.

Pharmacologic immunosuppression is essential for preventing organ rejection and controlling autoimmunity, but profoundly impairs humoral immunity, increasing the risk of vaccine failure and infection. The mechanisms by which immunosuppressive therapies disrupt human B cell responses remain poorly defined. Here, we iden...

Elizabeth A. Thompson, Alexis Figueroa, Katerina Roznik et al. · 0 citations
Open access Sep 2026

An altered B cell compartment distinguishes low antibody responders among people with HIV

Chronic HIV infection can leave persistent immune dysregulation despite effective antiretroviral therapy (ART), but how this altered immune landscape affects antibody induction and durability after antigen exposure remains unclear. We used SARS-CoV-2 infection and vaccination as a model of humoral immunity to a novel a...

Karli R. Redinger, Samuel B. Warner, A. Jamal et al. · 0 citations
Open access Jul 2026

Conserved CD4 T-cell responses correlate with antibody neutralization in solid organ transplant recipients after bivalent SARS-CoV-2 vaccination

The results emphasize the importance of conserved and cross-reactive responses in vaccine immunogenicity, providing a mechanism through which repeated boosting enhances vaccine immunogenicity in SOTRs and other immunocompromised populations.

Georgia Stavrakis, Katerina Roznik, Laila Stoddart et al. · 0 citations

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