Review
Open access
Aug 2026
Irisin in Cartilage Homeostasis: Molecular Mechanisms and Therapeutic Implications for Osteoarthritis
Osteoarthritis (OA) is a leading cause of disability worldwide, characterized by progressive joint degeneration driven by extracellular matrix (ECM) breakdown, chondrocyte apoptosis, and chronic low-grade inflammation. Despite the availability of several pharmacological and non-pharmacological interventions, no current...
Raffaella Rosy Vescio, M. Fiordalisi, L. Ambrosio et al.
· Journal of Functional Morpho... · 0 citations