Eline Pellaers

Optimalisatie van de block-and-lock strategie voor een HIV genezing: Het combineren van BRD4 modulatoren met LEDGINs

Infection with human immunodeficiency virus (HIV) is currently incurable because the virus integrates into the host genome of long-lived memory CD4+ T cells and can persist in a transcriptionally silent state, known as latency. Antiretroviral therapy (ART) effectively suppresses viral replication, restores CD4+ T cell...