Author

Eleonora Macchia

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Review Oct 2026

Targeting Cancer Hallmarks with Melatonin-based Analogues and Hybrids: From Pleiotropic Hormone to Multitarget Anticancer Agents.

Cancer remains one of the leading causes of mortality worldwide and represents a multifactorial disease characterized by the dysregulation of multiple interconnected biological processes, including uncontrolled cell proliferation, resistance to apoptosis, metabolic reprogramming, angiogenesis, chronic inflammation, imm...

Alexia Barbarossa, Antonio Carrieri, Eleonora Macchia et al. · Mini-Reviews in Medical Chem... · 0 citations

Review Open access Aug 2026

PROTAC-Based Strategies in Neurodegenerative Diseases: Challenges and Perspectives

This review summarizes recent advances in chemical protein degradation strategies for neurodegenerative disorders and highlights potential future perspectives of multifunctional PROTACs for therapeutic development.

Pasquale Degennaro, Imane Ghafir El Idrissi, Rosa Purgatorio et al. · Pharmaceuticals · 0 citations