Skip to content

Author

Eleanor Y. Chen

2 papers indexed here

We haven’t gathered this author’s papers yet. Follow them and we’ll fetch their work.

Not the right person? Other researchers publish under this name.

Open access Aug 2026

MAPK-driven MYC/p21 axis controls senescence bypass and BCL-XL dependence in vincristine-resistant rhabdomyosarcoma

Summary Therapy resistance remains the primary cause of treatment failure in rhabdomyosarcoma (RMS), the most common pediatric soft tissue sarcoma, yet underlying mechanisms are poorly understood. Using vincristine-resistant fusion-negative RMS models, RNA sequencing, genetic perturbations, and a syngeneic zebrafish tu...

Ya-Dong Wang, Andrea D. Largent, Dorothy Lee et al. · 0 citations
Jul 2026

Abstract B042: A differentiation-driven migration program in rhabdomyosarcoma (RMS) is governed by a BRD1-MYOG transcriptional axis

This work identified BRD1, a bromodomain-containing transcriptional regulator, as a previously unrecognized driver of RMS cell migration and defined a previously unrecognized regulatory circuit in which BRD1 promotes a MYOG-driven, differentiation-associated migratory state.

Andrea D. Largent, Yadong Wang, Abraham Hengyucius et al. · 0 citations

We use cookies to run the site and, with your consent, for analytics and to show ads. See our Cookie Policy.