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BACKGROUND Cardiac involvement in systemic amyloid A (AA) amyloidosis is traditionally considered rare. Respectively, contemporary data describing cardiac characteristics of patients with systemic AA amyloidosis are scarce. METHODS All patients with a diagnosis of systemic amyloidosis were identified from electronic...
BACKGROUND Cardiomyopathy significantly impacts maternal health worldwide. Artificial intelligence-enabled electrocardiograms (AI-ECG) have shown effectiveness in detecting left ventricular systolic dysfunction (LVSD) in adults and limited obstetric cohorts; however, broad validation in diverse obstetric populations re...
In patients with heart failure and advanced chronic kidney disease, CCBs use was associated with improved survival, supporting their potential role as a safe adjunctive therapy for blood pressure control in this high-risk population.
Abstract Aims Hypertrophic cardiomyopathy (HCM) remains underdiagnosed due to limited access to expert imaging. We developed and validated a deep-learning (DL)-based echocardiographic model adaptable to point-of-care ultrasound (POCUS) for scalable HCM screening. Methods and results We retrospectively analysed 134 956...
In asymptomatic adults without structural heart disease, the clinical determinants and long-term prognostic trajectories of ectopy exhibit a profound chamber-specific divergence and stands out as a powerful, independent marker of intrinsic electrical vulnerability and long-term cardiovascular risk.
Frailty fundamentally attenuates risk in HF, while multimorbidity stratifies prognosis only when physiological reserve is preserved, while multimorbidity stratifies prognosis only when physiological reserve is preserved.
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